The Greenville Little Theatre started in 1926 as the Greenville Artists Guild, presenting its first performances in the Ramsey Fine Arts Auditorium on the campus of the Greenville Woman's College. Two years later the theatre group renamed itself Community Little Theatre and later, Greenville Little Theatre.  They presented one to four plays annually for the next several years, rehearsing in either the Poinsett Hotel or the Christ Church Parish House. They performed in any local auditorium boasting a stage, such as Greenville High School and the Carolina Movie Theatre, but most frequently on the stage of the Woman's College. 

After WWII, the Greenville Little Theatre reorganized and began presenting plays in the Greenville High School Auditorium. An Air Force Glider Base movie theater on Lowndes Hill Road, vacant since the end of the war, was refurbished and became the group’s new home in 1948.  In 1967, the group moved to its present facility, the Charles E. Daniel Theatre, the location of the former Ramsay Fine Arts Auditorium.

Source: https://www.greenvilletheatre.org/history